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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
1998 1
1999 1
2000 3
2001 3
2002 5
2003 8
2004 16
2005 19
2006 27
2007 27
2008 30
2009 28
2010 33
2011 40
2012 42
2013 45
2014 20
2015 32
2016 18
2017 16
2018 24
2019 9
2020 14
2021 20
2022 15
2023 13
2024 4

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453 results

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Page 1
Pan-cancer analysis identifies BIRC5 as a prognostic biomarker.
Fäldt Beding A, Larsson P, Helou K, Einbeigi Z, Parris TZ. Fäldt Beding A, et al. BMC Cancer. 2022 Mar 25;22(1):322. doi: 10.1186/s12885-022-09371-0. BMC Cancer. 2022. PMID: 35331169 Free PMC article.
Interestingly, higher BIRC5 expression was associated with better OS in lung squamous cell carcinoma and ovarian serous cystadenocarcinoma. ...External validation showed that high BIRC5 expression was significantly associated with worse OS for breast-, lun …
Interestingly, higher BIRC5 expression was associated with better OS in lung squamous cell carcinoma and ovarian serous cystad …
BIRC5: A novel therapeutic target for lung cancer stem cells and glioma stem cells.
Kahm YJ, Kim RK. Kahm YJ, et al. Biochem Biophys Res Commun. 2023 Nov 19;682:141-147. doi: 10.1016/j.bbrc.2023.10.008. Epub 2023 Oct 4. Biochem Biophys Res Commun. 2023. PMID: 37806253 Free article.
Baculoviral inhibitor of apoptosis repeat containing 5 (BIRC5) is also known as survivin. BIRC5, a member of the apoptosis inhibitor (IAP) family, negatively regulates apoptosis or programmed cell death by inhibiting caspase activation. ...BIRC5 was simultane …
Baculoviral inhibitor of apoptosis repeat containing 5 (BIRC5) is also known as survivin. BIRC5, a member of the apoptosis inh …
Investigating subtypes of lung adenocarcinoma by oxidative stress and immunotherapy related genes.
Duan G, Huang C, Zhao J, Zhang Y, Zhao W, Dai H. Duan G, et al. Sci Rep. 2023 Nov 27;13(1):20930. doi: 10.1038/s41598-023-47659-8. Sci Rep. 2023. PMID: 38017020 Free PMC article.
Lung adenocarcinoma (LUAD) is one of the most widespread and fatal types of lung cancer. ...Through gene selection, we identified an optimal combination of 12 genes for predicting LUAD subtypes: ACP1, AURKA, BIRC5, CYC1, GSTP1, HSPD1, HSPE1, MDH2, MRPL13, NDU …
Lung adenocarcinoma (LUAD) is one of the most widespread and fatal types of lung cancer. ...Through gene selection, we identif …
BIRC5 Inhibition Is Associated with Pyroptotic Cell Death via Caspase3-GSDME Pathway in Lung Adenocarcinoma Cells.
Zhang Q, Chen X, Hu Y, Zhou T, Du M, Xu R, Chen Y, Tang P, Chen Z, Li J. Zhang Q, et al. Int J Mol Sci. 2023 Sep 28;24(19):14663. doi: 10.3390/ijms241914663. Int J Mol Sci. 2023. PMID: 37834111 Free PMC article.
Flow cytometry analysis, lactate dehydrogenase release (LDH) assay and Micro-PET imaging were performed in A549 cells and a mouse xenograft tumor to explore the function of BIRC5 in cell death of lung adenocarcinoma. We found that BIRC5 was up-regulated and r …
Flow cytometry analysis, lactate dehydrogenase release (LDH) assay and Micro-PET imaging were performed in A549 cells and a mouse xenograft …
alpha5-nAChR and survivin: Two potential biological targets in lung adenocarcinoma.
Zhang Y, Sun Y, Jia Y, Zhang Q, Zhu P, Ma X. Zhang Y, et al. J Cell Physiol. 2021 Mar;236(3):1787-1797. doi: 10.1002/jcp.29956. Epub 2020 Jul 28. J Cell Physiol. 2021. PMID: 33196129
Recent studies have shown that the overexpression of alpha5 nicotinic acetylcholine receptor (alpha5-nAChR) is associated with nicotine-related lung carcinogenesis. Survivin is one of the biomarkers of a worse prognosis for smoking-related lung cancer. The aim of th …
Recent studies have shown that the overexpression of alpha5 nicotinic acetylcholine receptor (alpha5-nAChR) is associated with nicotine-rela …
Prognostic Value of BIRC5 in Lung Adenocarcinoma Lacking EGFR, KRAS, and ALK Mutations by Integrated Bioinformatics Analysis.
Cao Y, Zhu W, Chen W, Wu J, Hou G, Li Y. Cao Y, et al. Dis Markers. 2019 Apr 9;2019:5451290. doi: 10.1155/2019/5451290. eCollection 2019. Dis Markers. 2019. PMID: 31093306 Free PMC article.
OBJECTIVE: This study was aimed at investigating the prognostic significance of Baculoviral IAP repeat containing 5 (BIRC5) in lung adenocarcinoma (LAD) lacking EGFR, KRAS, and ALK mutations (triple-negative (TN) adenocarcinomas). ...BIRC5 is a potential pred …
OBJECTIVE: This study was aimed at investigating the prognostic significance of Baculoviral IAP repeat containing 5 (BIRC5) in lun …
CircCAMSAP1 promotes non-small cell lung cancer proliferation and inhibits cell apoptosis by sponging miR-1182 and regulating BIRC5.
Wang Y, Li X, Wang H, Zhang G. Wang Y, et al. Bioengineered. 2022 Feb;13(2):2428-2439. doi: 10.1080/21655979.2021.2011639. Bioengineered. 2022. PMID: 35132928 Free PMC article.
However, BIRC5 without 3' untranslated regions (3'UTR) could reverse the influence of downregulated circCAMSAP1 on proliferation and apoptosis in NSCLC. Together, our findings reveal a novel mechanism by which the circCAMSAP1/miR-1182/BIRC5 axis promotes NSCLC progr …
However, BIRC5 without 3' untranslated regions (3'UTR) could reverse the influence of downregulated circCAMSAP1 on proliferation and …
Establishing a prognostic model based on immune-related genes and identification of BIRC5 as a potential biomarker for lung adenocarcinoma patients.
Ren Q, Li Q, Shao C, Zhang P, Hu Z, Li J, Wang W, Yu Y. Ren Q, et al. BMC Cancer. 2023 Sep 23;23(1):897. doi: 10.1186/s12885-023-11249-8. BMC Cancer. 2023. PMID: 37741993 Free PMC article.
BACKGROUND: Lung adenocarcinoma (LUAD) is an extraordinarily malignant tumor, with rapidly increasing morbidity and poor prognosis. ...Single-cell RNA sequencing revealed that the expression level of BIRC5 was significantly high in T cells. Cell experiments further …
BACKGROUND: Lung adenocarcinoma (LUAD) is an extraordinarily malignant tumor, with rapidly increasing morbidity and poor prognosis. . …
Lung development, repair and cancer: A study on the role of MMP20 gene in adenocarcinoma.
Mok PL, Anandasayanam ANK, Oscar David HM, Tong J, Farhana A, Khan MSA, Sivaprakasam G, Koh AE, Alzahrani B. Mok PL, et al. PLoS One. 2021 Apr 29;16(4):e0250552. doi: 10.1371/journal.pone.0250552. eCollection 2021. PLoS One. 2021. PMID: 33914777 Free PMC article.
The role of MMP20 is not well studied in lung organogenesis, however, it was previously shown to be present at high level in lung adenocarcinoma. The current study aimed to identify the functional properties of MMP20 on cell proliferation and motility in a lung …
The role of MMP20 is not well studied in lung organogenesis, however, it was previously shown to be present at high level in lung …
ABBV-184: A Novel Survivin-specific TCR/CD3 Bispecific T-cell Engager is Active against Both Solid Tumor and Hematologic Malignancies.
Chervin AS, Stone JD, Konieczna I, Calabrese KM, Wang N, Haribhai D, Dong F, White MK, Rodriguez LE, Bukofzer GT, Ellis PA, Cosgrove C, Hecquet C, Clarin JD, Palma JP, Reilly EB. Chervin AS, et al. Mol Cancer Ther. 2023 Aug 1;22(8):903-912. doi: 10.1158/1535-7163.MCT-22-0770. Mol Cancer Ther. 2023. PMID: 37294945
Here we describe the generation and preclinical evaluation of ABBV-184, a novel TCR/anti-CD3 bispecific composed of a highly selective soluble TCR that binds a peptide derived from the oncogene survivin (BIRC5) bound to the class I MHC allele human leukocyte antigen (HLA)- …
Here we describe the generation and preclinical evaluation of ABBV-184, a novel TCR/anti-CD3 bispecific composed of a highly selective solub …
453 results